Latest Articles
Practical perspectives on supplement claims, scientific evidence, product risk, regulatory issues, food safety, and the decisions that depend on getting the science right.
Can You Really Call Berberine “Nature’s Ozempic”?
Calling berberine “Nature’s Ozempic” may sound persuasive, but the clinical evidence does not support the kind of weight-loss expectations that comparison creates.
The 7-OH Lesson: When Product Innovation Creates Regulatory Risk
7-OH shows how concentrating a naturally occurring compound can turn a product-development decision into a serious scientific and regulatory risk.
Your Product Has Studies. But Do They Support Your Claims?
Having studies is not the same as having evidence for the claims on your label, website, or advertising, and that gap can become expensive.
Creatine Beyond Muscle: What the Latest Clinical Trials Reveal About Brain Health, Aging, and Sleep Resilience
Creatine may support some aspects of memory and mental performance, but the benefits are not the same for everyone. This article explains what current clinical trials suggest about brain function, sleep deprivation, aging, diet, menopause, and who may be most likely to benefit.
The Probiotic Strain Problem: Why the Species Name on Your Label Isn’t Enough
Different probiotic strains can produce different effects, so evidence from one strain may not support another. This article explains where probiotic claim substantiation gaps arise and why species-level evidence may not be enough.
Structure/Function Claims Under DSHEA: What’s Allowed, What’s Not, and Why It Matters
Structure/function claims may be permitted under DSHEA, but compliant wording alone is not enough. Learn where supplement claims become vulnerable when the scientific evidence does not support what the product promises.
Why Most Supplement Claims Won’t Survive FDA Scrutiny — And What to Do About It
Supplement claims can look well supported until the science is examined closely. Learn why dose, ingredient, population, endpoints and the totality of evidence can determine whether a claim survives scrutiny.
Have a Scientific Question With Something at Stake?
If a claim, ingredient, product, or scientific question carries financial, regulatory, legal, or reputational consequences, we can help you understand what the evidence supports and what to do next.